Methyl quinoline-2-carboxylate
CAS No. 19575-07-6
Methyl quinoline-2-carboxylate( —— )
Catalog No. M37047 CAS No. 19575-07-6
Methyl quinoline-2-carboxylate (Methyl 2-quinolinecarboxylate) inhibits the binding of Mycobacterium tuberculosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameMethyl quinoline-2-carboxylate
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NoteResearch use only, not for human use.
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Brief DescriptionMethyl quinoline-2-carboxylate (Methyl 2-quinolinecarboxylate) inhibits the binding of Mycobacterium tuberculosis.
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DescriptionMethyl quinoline-2-carboxylate (Methyl 2-quinolinecarboxylate) inhibits the binding of Mycobacterium tuberculosis.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number19575-07-6
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Formula Weight187.19
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Molecular FormulaC11H9NO2
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Purity>98% (HPLC)
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Solubility——
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SMILESCOC(=O)C1=NC2=CC=CC=C2C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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SMARt-420
SMARt-420 (BDM 41420) is a small molecule that can fully reverses ethionamide-acquired resistance and clears ethionamide-resistant M. tuberculosis infection in mice.
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NITD-916
NITD-916 is a novel, direct inhibitor of the mycobacterial enoyl-reductase InhA with IC50 of 0.57 uM.
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Chebulinic acid
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.Chebulinic acid obviously inhibited HQ/Cu(II)- and H(2)O(2)/Cu(II)-mediated pBR322 DNA strand breaks. When MRC-5 cells were treated with HQ/Cu(II), the presence of Chebulinic acid inhibited HQ/Cu(II)-mediated double-strand breaks of genomic DNA.
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